Zontivity is a newer generation anticoagulant medication. Several anticoagulant medications have been associated with an increase in the risk of side effects, including uncontrolled bleeding and hemorrhage in the brain. Lawsuits have been filed against the manufacturers of some anticoagulant drugs, alleging these medications caused serious injuries and/or death to some patients.
Anticoagulant medications are used to prevent heart attacks, stroke and preventing the patient’s blood from clotting. A serious side effect linked to this medication is that even a minor cut could potentially result in uncontrolled bleeding, which could be fatal.
Warfarin has been linked to an increased risk of bleeding, however, there is a reversal agent available for Warfarin, if medical attention is received on time. The newer generation anticoagulant medications are linked to an increase of uncontrolled bleeding, with no current antidote available.
Zontivity (also known as vorapaxar) received FDA approval in 2014 as an anticoagulant to prevent stroke, myocardial infarction and cardiovascular death in certain patients. It is the first in a class of drugs called protease-activated receptor-1 antagonists.
There was at least one study, known as a TRACER, stopped early because of a suggested increased risk of major bleeding, including intracranial hemorrhage, in patients who received Zontivity, according to FDA briefing documents. Furthermore, patients in another study called TRA2P who had a history of stroke stopped being enrolled because of a potential increased risk of intracranial hemorrhage.
The TRA2P study suggested an increased risk of moderate or severe bleeding and further suggested an increased risk of intracranial hemorrhage. A news release from the FDA notes that Zontivity increases the risk of bleeding, (including life-threatening and fatal bleeding) with bleeding being the most commonly reported adverse reaction linked to Zontivity.
If you or a loved one has suffered injuries or death after the use of Zontivity, you may be entitled to compensation for your damages. Contact one of our experienced Gacovino Lake attorneys at 1-800-246-HURT (4878) for more information.