Canagliflozin (trade name Invokana or Sulisent) is a drug of the gliflozin class or subtype 2 sodium-glucose transport (SGLT-2) inhibitors used for the treatment of type 2 diabetes. It was developed by Mitsubishi Tanabe Pharma and is marketed under license by Janssen, a division of Johnson & Johnson.
Canagliflozin was approved by the FDA on March 29, 2013, and became the first SGLT2 inhibitor in the United States.
How Invokana Works
Invokana works by blocking the reabsorption of glucose by the kidney, increasing glucose excretion, and lowering blood glucose levels in diabetics who have elevated blood glucose levels. Its safety and effectiveness were evaluated in nine clinical trials involving over 10,285 patients with type 2 diabetes. The trials showed improvement in hemoglobin A1c levels (a measure of blood sugar control) and fasting plasma glucose (blood sugar) levels.
Dangerous Side Effects of Januvia
The most common side effects of Invokana are vaginal yeast infection (vulvovaginal candidiasis) and urinary tract infection. Because Invokana is associated with a diuretic effect, it can cause a reduction in intravascular volume leading to orthostatic or postural hypotension (a sudden fall in blood pressure when standing up). This may result in symptoms such as dizziness or fainting, and is most common in the first three months of therapy.
Below are some of the side effects that have been reported with INVOKANA®:
- Dehydration due to the loss of body water and salt
- Kidney problems
- Vaginal yeast infection
- Yeast infection of the penis
- Risk of bone fracture
- Potentially serious urinary tract infection
- Changes in urination, including the urgent need to urinate more often, in larger amounts, or at night
- High potassium in the blood (hyperkalemia)
- Low blood sugar (hypoglycemia)
- Increases in cholesterol
Filing a Lawsuit if Harmed
Some individuals may have grounds to file a lawsuit against the manufacturer of Invokana, if they suffer serious side effects like Ketoacidosis or bone fractures.
If you’ve been prescribed Invokana and suffered serious health consequences as a result, our lawyers can help you explore legal options that might be available. The manufacturer may be liable for damages if seriously harmed.
Pursuing a Defective Drug Claim with our Invokana Lawyers
If you are interested in pursuing a defective drug claim, the first thing that you will have to prove is that Invokana caused your health problems and that your health problems would not have occurred but for your use of the drug. In order to prove this claim, utilizing the services of our attorneys is in your best interest.
At Gacovino, Lake, & Associates P.C., our attorneys can help explore and prove the liability of a defective drug’s manufacturer. If you’re a victim of harmful side effects, we can help get the compensation to which you’re entitled. Call us today at 800-550-0000 or use our contact form to set up a consultation so you can get started today.